EMERGING CASES OF MULTI DRUG RESISTANT TUBERCULOSIS

Drug-resistant tuberculosis: emerging treatment options

Multidrug-resistant tuberculosis has emerged worldwide, with an increasing incidence due to failure of implementation of apparently effective first-line antituberculous therapy as well as primary infection with drug-resistant strains. Failure of current therapy is attributed to a long duration of treatment leading to nonadherence and irregular therapy, lack of patient education about the diseas...

Pattern of Adverse Effects of Drugs Used to Treat Multi Drug Resistant Tuberculosis

During treatment of multi drug resistant tuberculosis (MDR-TB), patients suffer from many adverse effects. Severe adverse effects may lead to refusal and discontinuation of treatment. Though national tuberculosis control programs are generally well structured, they do not collect information on adverse effects of drug directly. This study had been designed to observe the pattern of adverse effe...

Multi-drug resistant tuberculosis in Northern Pakistan.

OBJECTIVE To determine the resistance pattern of Mycobacterium tuberculosis isolates in Rawalpindi-Islamabad. METHODS The study was carried out at the Department of Microbiology, Armed Forces Institute of Pathology, Rawalpindi between September 2000 and August 2002. We examined 1359 pulmonary and extra-pulmonary specimens from suspected cases of tuberculosis. The radiometric Bactec 460 TB sys...

Multidrug- and extensively drug-resistant tuberculosis: an emerging threat.

Emerging Public Health Issues in Drug-Resistant Tuberculosis

Drug Resistance is a major challenge in the control of Tuberculosis which itself re‐ mains a global public health problem. Resistance is commonly encountered as MDR TB but a subset, XDR TB which has about a comparatively fivefold increase in mortal‐ ity is now identified in 84 countries worldwide and increasing rates are currently re‐ ported from 65 countries. The actual burden of MDR TB is unk...